• Asparaginase-Associated Pancreatitis in Acute Lymphoblastic Leukemia: Results From the NOPHO ALL2008 Treatment of Patients 1-45 Years of Age 

      Rank, Cecilie Utke; Wolthers, Benjamin Ole; Grell, Kathrine; Albertsen, Birgitte K.; Frandsen, Thomas L.; Overgaard, U.; Toft, Nina; Nielsen, Ove Juul; Wehner, Peder S.; Harila-Saari, Arja; Heyman, Mats M.; Malmros, Johan; Abrahamsson, Jonas; Norén-Nyström, Ulrika; Tomaszewska-Toporska, Beata; Lund, Bendik; Jarvis, Kirsten Brunsvig; Quist-Paulsen, Petter; Vaitkeviciene, Goda; Griškevičius, Laimonas; Taskinen, Mervi; Wartiovaara-Kautto, Ulla; Lepik, Kristi; Punab, Mari; Jónsson, Ólafur G.; Schmiegelow, Kjeld (Journal article; Peer reviewed, 2020)
      PURPOSE Asparaginase-associated pancreatitis (AAP) is common in patients with acute lymphoblastic leukemia (ALL), but risk differences across age groups both in relation to first-time AAP and after asparaginase re-exposure ...
    • Bereaved parents’ quality of life: resilience and professional support 

      Rasouli, Omid; Vegsund, Hilde Kristin; Eilegård, Alexandra; Hjemdal, Odin; Reinfjell, Trude; Moksnes, Unni Karin; Lund, Bendik; Eilertsen, Mary-Elizabeth B (Peer reviewed; Journal article, 2021)
      Objectives: The study aimed to compare the quality of life (QoL) among cancer-bereaved parents with a control group and explore how resilience and support from healthcare professionals associated with QoL of parents 2–8 ...
    • Genetic predisposition to PEG-asparaginase hypersensitivity in children treated according to NOPHO ALL2008 

      Højfeldt, Sofie G; Wolthers, Benjamin Ole; Tulstrup, Morten; Abrahamsson, Jonas; Gupta, Ramneek; Harila-Saari, Arja; Heyman, Mats; Henriksen, Louise T; Jonsson, Olafur G.; Lähteenmäki, Päivi M.; Lund, Bendik; Pruunsild, Kaie; Vaitkeviciene, Goda; Schmiegelow, Kjeld; Albertsen, Birgitte K. (Peer reviewed; Journal article, 2018)
      Asparaginase is essential in childhood acute lymphoblastic leukaemia (ALL) treatment, however hypersensitivity reactions to pegylated asparaginase (PEG-asparaginase) hampers anti-neoplastic efficacy. Patients with ...
    • Health-related quality of life and psychological distress in young adult survivors of childhood cancer and their association with treatment, education, and demographic factors 

      Fagervoll, Janne Strand; Sund, Anne Mari; Zeltzer, Lonnie K.; Ådnanes, Marian; Jensberg, Heidi; Eikemo, Terje Andreas; Lund, Bendik; Hjemdal, Odin; Reinfjell, Trude (Journal article; Peer reviewed, 2017)
      Purpose This study investigated health-related quality of life (HRQOL) and psychological distress among young adult (YA) survivors of childhood cancer and the association of these measures with treatment, education, and ...
    • Host Genome Variation and Toxicity in Childhood Acute Lymphoblastic Leukaemia 

      Lund, Bendik (Doktoravhandlinger ved NTNU, 1503-8181; 2014:41, Doctoral thesis, 2014)
      Kreft er den vanligste medisinske dødsårsaken hos barn mellom 1 og 15 år. Akutt lymfatisk leukemi (ALL) er den vanligste kreftformen hos barn og i Norge får ca. 30-40 barn ALL hvert år. Behandlingen strekker seg over 2,5 ...
    • Humoral immunity and revaccination in childhood cancer 

      Tangenes, Mathias (Master thesis, 2017)
      Background: Chemotherapy treatment for childhood cancer impair the cellular and humoral immune system in various degrees and affects the previous protection of childhood vaccination. Studies have shown protective antibody ...
    • The Norwegian childhood cancer biobank 

      Hermansen, Johanne Uthus; Wojcik, Dorota; Robinson, Nina; Pahnke, Jens; Haugland, Hans Kristian; Jamtøy, Ann-Helen; Flægstad, Trond; Halvorsen, Hanne; Lund, Bendik; Baumbusch, Lars Oliver; Munthe-Kaas, Monica Cheng (Peer reviewed; Journal article, 2021)
      Background The rapidly expanding era of “omics” research is highly dependent on the availability of quality-proven biological material, especially for rare conditions such as pediatric malignancies. Professional biobanks ...
    • Phosphatase of regenerating liver-3 (PRL-3) is overexpressed in classical Hodgkin lymphoma and promotes survival and migration 

      Hjort, Magnus Aasved; Hov, Håkon; Abdollahi, Pegah; Vandsemb, Esten; Fagerli, Unn-Merete; Lund, Bendik; Slørdahl, Tobias Schmidt; Børset, Magne; Rø, Torstein Baade (Journal article; Peer reviewed, 2018)
      Background Phosphatase of regenerating liver-3 (PRL-3) is implicated in oncogenesis of hematological and solid cancers. PRL-3 expression increases metastatic potential, invasiveness and is associated with poor prognosis. ...
    • Phosphatase of regenerating liver-3 as a target for treatment of B cell malignancies 

      Hjort, Magnus Aassved (Doctoral theses at NTNU;2018:241, Doctoral thesis, 2018)
      PRL-3 som et angrepsmål i behandlingen av B-cellekreft Akutt lymfatisk leukemi (ALL), Hodgkin lymfom (HL) og myelomatose er kreftsykdommer som oppstår fra B-lymfocytter. Disse cellene er en del av kroppens immunforsvar. ...
    • Phosphatase of regenerating liver-3 is expressed in acute lymphoblastic leukemia and mediates leukemic cell adhesion, migration and drug resistance 

      Hjort, Magnus Aassved; Abdollahi, Pegah; Vandsemb, Esten Nymoen; Fenstad, Mona H.; Lund, Bendik; Slørdahl, Tobias Schmidt; Børset, Magne; Rø, Torstein Baade (Journal article; Peer reviewed, 2017)
      Phosphatase of regenerating liver-3 (PRL-3/PTP4A3) is upregulated in multiple cancers, including BCR-ABL1- and ETV6-RUNX-positive acute lymphoblastic leukemia (ALL). With this study, we aim to characterize the biological ...
    • The WE-Study: does botulinum toxin A make walking easier in children with cerebral palsy?: Study protocol for a randomized controlled trial 

      Brændvik, Siri Merete; Roeleveld, Karin; Andersen, Guro Lillemoen; Raftemo, Anne Elisabeth Ross; Ramstad, Kjersti; Majkic-Tajsic, Jasmina; Lamvik, Torarin; Lund, Bendik; Follestad, Turid; Vik, Torstein (Journal article; Peer reviewed, 2017)
      Background Intramuscular injections of botulinum toxin A (BoNT-A) have been a cornerstone in the treatment of spasticity for the last 20 years. In Norway, the treatment is now offered to two out of three children with ...